Progesterone synthesis by pig corpus luteum tissue during superfusion
نویسندگان
چکیده
منابع مشابه
Regulation of progesterone synthesis and action in bovine corpus luteum.
The main function of the corpus luteum (CL) is to synthesize and secrete progesterone (P4), which regulates the duration of the estrous cycle and maintains of pregnancy in many species. Both synthesis and action of this hormone is regulated by many luteotropic and luteolytic factors. Progesterone also affects its own synthesis by regulation of the activity and genes expression of crucial enzyme...
متن کاملMolecular regulation of progesterone synthesis in the bovine corpus luteum
In bovine luteal cells, progesterone can directly affect its own synthesis by increasing the activity of 3β-HSD. The effect of progesterone on its own secretion coincides with increased expression of the genes for 3βHSD, StAR, and cytochrome P450scc. Therefore, progesterone regulates its own synthesis by affecting the activity of the enzymes that take part in luteal steroidogenesis, and also by...
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Studies comparing the regressing corpus luteum with the rescued corpus luteum have demonstrated that human chorionic gonadotrophin (hCG) has effects on cell types that do not express hCG receptors. As progesterone synthesis is hCG dependent and the corpus luteum has been shown to express genomic progesterone receptors, progesterone is a candidate molecule for these paracrine effects. This study...
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Whereas mare corpus luteum does not produce androgens or estrogens in vivo, the incubation of mare corpus luteum microsomes with progesterone and NADPH resulted in 17 alpha-hydroxyprogesterone and estrogen production with a small yield of androstenedione. In the presence of an aromatase inhibitor (4-hydroxyandrostenedione), 17 alpha-hydroxyprogesterone and androstenedione were accumulated. Arom...
متن کاملSuperfusion of pituitary tissue
Tilapia (Oreochromis mossambicus] teleostei) melanin-concentrating hormone gene-related peptide (tMgrp) was tested for tropic actions on adenocorticotropin hormone (ACTH) and a melanocyte s t im u la t in g ho rm one ( a M S H ) producing cells in the tilapia pituitary gland in vitro. Up to 100 pM synthetic tilapia Mgrp (tMgrp) had no effect on a -M S H release from tilapia neurointermediate lo...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1975
ISSN: 0306-3283
DOI: 10.1042/bj1500301